Scientific Publications

Shamini has conducted numerous clinical trials and basic science research in the areas of integrative medicine and psychoneuroimmunology.  A complete list of her publications can be found here through this Google Scholar link.  Below are a few highlighted scientific publications (Click on the title of the article to access the PDF).

A randomized controlled trial of mindfulness meditation versus relaxation training: Effects on distress, positive states of mind, rumination, and distraction.

S Jain, SL Shapiro, S Swanick, SC Roesch, PJ Mills, I Bell, GER Schwartz

Annals of Behavioral Medicine (2007); 33 (1), 11-21

This landmark study was the first randomized controlled trial to compare a mindfulness meditation intervention with an active relaxation intervention, and examine cognitive mechanisms of action that might separate mindfulness meditation from relaxation processes. Dr. Jain and her colleagues found that mindfulness was unique from relaxation in its ability to reduce ruminative and distractive thinking, and that these reductions in rumination drove decreases in distress for those who were being trained in mindfulness meditation.

Indo-Tibetan Philosophical and Medical Systems: Perspectives on the Biofield

Shamini Jain, PhD, Jennifer Daubenmier, PhD, David Muehsam, PhD, Lopsang Rapgay, PhD, and Deepak Chopra, MD, FACP

Glob Adv Health Med (2015) Nov; 4(Suppl): 16–24.  Published online 2015 Nov 1. doi:  10.7453/gahmj.2015.026.suppl

In this paper, we discuss Vedic, Jain and Tibetan Buddhist models of consciousness and how these traditions' philosophical and medical systems related to current Western concepts in health and healing.

Complementary medicine for fatigue and cortisol variability in breast cancer survivors.

S Jain, D Pavlik, J Distefan, RRL Bruyere, J Acer, R Garcia, I Coulter

Cancer (2012) 118 (3), 777-787

This randomized controlled study with fatigued breast cancer survivors examined the effects of hands-on-healing for reducing fatigue and improving quality of life and physiological function, as compared to a mock healing group and a wait-list control group. Placebo variables were carefully measured and examined as predictors of response. The study found that the actual healing group showed clinically and statistically significant reductions in fatigue, as well as improvements in cortisol variability. Placebo factors predicted changes in quality of life, but not changes in cortisol variability.

Healing Touch with Guided Imagery for PTSD in returning active duty military: a randomized controlled trial.

S Jain, GF McMahon, P Hasen, MP Kozub, V Porter, R King, EM Guarneri

Military Medicine (2012) ; 177 (9), 1015-1021

This randomized controlled trial examined the effects of Healing Touch combined with Guided Imagery compared to treatment as usual in active duty military at a military base. Results showed statistically and clinically significant decreases in PTSD, depression, and cynicism for the treatment group compared to the control group.

Effects of perceived stress and uplifts on inflammation and coagualibility.

Jain S, Mills PJ, von Känel R, Hong S, Dimsdale JE

Psychophysiology (2007); Jan 44(1):154-60

This study examined the effects of perceptions of daily events as either stressful (hassles) or positive (uplifts) on immune and blood markers in otherwise healthy individuals.  Results from the study indicated that increased perceptions of “hassles” are associated with increases in inflammation and hypercoagulabilty, and independently, increased perception of life events as “uplifts” are associated with decreased hypercoagulability.

Biofield therapies: helpful or full of hype? A best evidence synthesis.

S Jain, PJ Mills

International Journal of Behavioral Medicine (2009); 17 (1), 1-16

This systematic review examined the evidence for 66 clinical studies of biofield therapies (such as Reiki, Healing Touch and others) in a variety of patients. Results indicated that these therapies showed strong evidence for reducing pain, moderate evidence for reducing anxiety in hospitalized populations and moderate evidence for reducing negative behavior symptoms in dementia.